SBIR Topic Watch

Open SBIR and STTR topics

361 topics, open or in pre-release, read from DSIP and SBIR.gov on Nov 12, 2026.

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CMMC requirements: Level 1 15Level 2 (Self) 95 what do the levels mean?
Level 1
Basic protection of Federal Contract Information: the 15 requirements of FAR 52.204-21. You assess yourself every year and post the result in SPRS.
Level 2
Protection of Controlled Unclassified Information: the 110 requirements of NIST SP 800-171 Rev. 2. "Self" means you assess yourself every three years; "C3PAO" means an accredited third-party assessor certifies you every three years. Both need a yearly affirmation.
Level 3
Level 2 certification plus 24 selected requirements of NIST SP 800-172, assessed by the government (DIBCAC) every three years.

CMMC is the Defense Department's cybersecurity certification; a topic that lists a level expects it by the time of award. This is a summary: the solicitation and 32 CFR Part 170 govern.

Showing 24 of 274 topics

NSF Open
Space
Topic # SP · released 2026-05-22

The Space topic seeks transformative technologies to create solutions for sustainable space exploration, habitation or industrialization that could also have a positive impact on human lives. Applicants should address known capability gaps ...

Deadline Jul 7, 2027 Closes in 237 days
NSF Open
Wireless Technologies
Topic # W · released 2026-05-22

The Wireless topic involves next-generation wireless communication technologies requiring systems with high data rates, low costs and that support a wide variety of applications and services while maintaining full mobility, minimum ...

Deadline Jul 7, 2027 Closes in 237 days
HHS ARPA-H Open
Versatile Bioadhesives
Topic # ARPA-H · released 2026-06-11

The purpose of this topic is to develop next-generation bioadhesive platforms that can safely and reliably seal, bond, and repair a wide range of tissues in challenging clinical conditions, including wet, bloody, and mechanically dynamic ...

Deadline Sep 30, 2027 Closes in 322 days
HHS ARPA-H Open
Universal Platform for Living Adaptive Toxin-removal (UNI-PLAT)
Topic # ARPA-H · released 2026-06-11

The purpose of this topic area is to catalyze the development of a universal, “plug-and-play” synthetic biology platform that enables next-generation microbial chassis capable of performing a broad array of programmable functions. While ...

Deadline Sep 30, 2027 Closes in 322 days
HHS ARPA-H Open
ARPA-H Lineage Topic
Topic # ARPA-H · released 2026-06-11

he purpose of this topic supports the advancement, commercialization, and translation of technologies that originated from ARPA-H funded efforts. It is intended to help small businesses and startups develop viable products based on these ...

Deadline Sep 30, 2027 Closes in 322 days